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LE cell
An LE cell is a neutrophil or macrophage that has phagocytized (engulfed) the denatured nuclear material of another cell.〔http://www.merriam-webster.com/medical/le%20cell〕 The denatured material is an absorbed hematoxylin body (also called an LE body).〔(similima.com > Autoimmunity ) By Muhammed Muneer. Retrieved Mars 2011〕 They are a characteristic of lupus erythematosus,〔http://www.drugsfreelist.com/health_articles/4002/LE_Cell_Test__Lupus_erythematosus_test__〕 but also found in similar connective tissue disorders. The LE cell was discovered in bone marrow in 1948 by Hargraves ''et al.''〔Hargraves M, Richmond H, Morton R. ''Presentation of two bone marrow components, the tart cell and the LE cell.'' Mayo Clin Proc 1948;27:25–28.〕 Classically, the LE cell is analyzed microscopically, but it is also possible to investigate this phenomenon by flow cytometry. ==References==
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